Biotin and derivatives
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | MFCD23381190 | >97.0% | 501.49 g/mol | C20H31N5O10 | 50 MG
DOTA-NHS-ester is an activated N-hydroxysuccinimide (NHS) ester of the DOTA chelator used to conjugate DOTA to amine-containing molecules for radiolabeling and imaging applications. It is intended for research use and is typically used to prepare peptide or antibody conjugates for small-animal PET, SPECT, and CT studies.
- Activated NHS-ester for amine conjugation.
- Used to prepare conjugates for PET, SPECT, and CT imaging.
- Suitable for labeling radiotherapeutic agents and imaging probes.
- Molecular weight approximately 501.49 g/mol.
- Stored sealed and away from moisture; in solvent: -80°C for 6 months, -20°C for 1 month.
Medchemexpress LLC Bis-PEG13-NHS ester | 2221949-00-2 | MFCD21363287 | 98.0% | 884.92 | C38H64N2O21 | 50 MG
Bis-PEG13-NHS ester is a bifunctional PEG-based linker containing N-hydroxysuccinimide (NHS) ester reactive groups that enable efficient amine conjugation; it is used as a cleavable linker in antibody-drug conjugate and PROTAC synthesis and for general bioconjugation chemistry.
- contains N-hydroxysuccinimide (NHS) ester reactive groups.
- functions as a cleavable linker for ADC and PROTAC synthesis.
- molecular formula C38H64N2O21, molecular weight 884.92.
- cas number 2221949-00-2 for unambiguous identification.
- purity 98.0% suitable for research applications.
- available in a 50 MG pack suitable for lab-scale synthesis.
- intended for research use only; not for human or clinical use.
Medchemexpress LLC Bis-PEG6-NHS ester | 1526718-98-8 | 98.0% | 576.55 g/mol | C24H36N2O14 | 50 MG
Bis-PEG6-NHS ester is a PEG-based bifunctional linker bearing two N-hydroxysuccinimide (NHS) ester termini separated by a six-unit polyethylene glycol spacer. It is used to conjugate amine-containing ligands in the synthesis of PROTACs and as a cleavable linker for antibody-drug conjugates (ADCs).
- High purity (98.0%).
- Two NHS ester termini for efficient amine coupling.
- PEG6 spacer provides aqueous solubility and conformational flexibility.
- Suitable as a cleavable linker in ADC construction and for PROTAC linker design.
- Store sealed at -20 °C, away from moisture; unstable in solution, prepare fresh as needed.
Medchemexpress LLC PC biotin-PEG3-NHS ester | 2353409-93-3 | 840.89 | C36H52N6O15S | 10 MG
PC Biotin-PEG3-NHS ester is a cleavable 3-unit polyethylene glycol (PEG3) biotinylation reagent bearing an N-hydroxysuccinimide (NHS) active ester. It is used as a cleavable ADC linker and for biotinylation of primary amines in peptides, proteins, and other biomolecules to enable affinity capture or detection. The product is supplied as a solid and should be stored as a powder at -20°C; solutions have shorter storage lifetimes. Handle only by trained personnel for research use.
- Cleavable PEG3 biotin linker for ADC conjugation and labeling
- Reactive NHS ester for selective labeling of primary amines
- Molecular weight 840.89 and formula C36H52N6O15S
- Solid appearance; store powder at -20°C for long-term stability
- Intended for laboratory research use only
Medchemexpress LLC N-Mal-N-bis(PEG2-NHS ester) | 2182601-73-4 | 98.9% | C29H38N4O15 | 25 MG
N-Mal-N-bis(PEG2-NHS ester) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs employ two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. These compounds leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Supports synthesis of PROTACs
- Exploits ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Store at -20°C, protected from light and under nitrogen
- Soluble in DMSO (100 mg/mL)
eMolecules 1688598-83-5 | NHS-PEG1-SS-PEG1-NHS | Ambeed436.410 | C14H16N2O10S2 | 97.000 | O=C(OCCSSCCOC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1g | 592288798
NHS-PEG1-SS-PEG1-NHS | Ambeed | 1688598-83-5436.410 | C14H16N2O10S2 | 97.000 | O=C(OCCSSCCOC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 1g | 592288798
Medchemexpress LLC Azido-PEG12-NHS ester | 2363756-50-5 | 98.0% | C31H56N4O16 | 50 MG
Azido-PEG12-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Medchemexpress LLC BHQ-2 NHS | 916753-62-3 | 97.7% | 603.58 | 50 MG
BHQ-2 NHS is a dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester. It has a wide and intense quenching range from 560-670 nm, making it useful as an acceptor in fluorescence resonance energy transfer (FRET) applications with orange to far-red emitting dyes. The NHS ester can be used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
- Dark quencher with no native emission due to the polyaromatic-azo backbone and a terminal NHS ester.
- Wide and intense quenching range from 560-670 nm.
- Useful as an acceptor in fluorescence resonance energy transfer (FRET) applications in conjunction with orange to far-red emitting dyes.
- NHS ester can be applied to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Chemscene ChemScene | Azido-PEG11-amine | 100MG | CS-0114594 | 0.95 | 1800414-71-4| MFCD08274605 | 570.67
ChemScene | Azido-PEG11-amine | 100MG | CS-0114594 | 0.95 | 1800414-71-4| MFCD08274605 | 570.67